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These target genes encompass a wide range of antioxidant enzymes and GSH synthesis-related genes, including the key System Xc component SLC7A11

The answer is, though rare, yes, there are

Urgent intervention involves external ventricular drainage placement, a procedure associated with a 15% incidence of tract hemorrhage, albeit mostly clinically inconsequential (9)

Regular exercise can lower the accumulation of reactive oxygen species (ROS) and boost the negative feedback mechanism of the HPA axis, restoring normal stress responses

Y.BoussetL.LiangX.TangJ.et al (2021)

The Clinical Assessment, Treatment, and Prevention of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis: Clinical Practice Guidelines by the Infectious Diseases Society of America